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Research Review

Showing 1–1 of 1 articles · Keyword: Lipid-based delivery Clear keyword

BioMed Research International.2014ReviewNon-viral Gene Delivery

1. Lipid Nanoparticles as Carriers for RNAi against Viral Infections Current Status and Future Perspectives

Torrecilla J, Rodríguez-Gascón A, Solinís Má, Del Pozo-Rodríguez A

Naked RNAi molecules are rapidly degraded by serum nucleases and cannot readily cross cell membranes because of their negative charge. Effective delivery systems are therefore required to exploit RNAi for antiviral therapy. Lipid nanoparticles (LNPs) are attractive because they are relatively safe, simple to produce…

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