Non-viral Gene Delivery
How nucleic acid payloads reach the cytosol without a viral vector — covering lipid, polymer, hybrid and inorganic reagents, and extracellular vesicles.
- Lipid-Based ReagentsSynthetic or natural lipid formulations used to encapsulate and transport cargo into cells.
- Polymer-Based ReagentsCationic or biodegradable polymers that bind nucleic acids, forming complexes that can enter cells.
- Hybrid ReagentsDelivery systems that combine different components to exploit the advantages of each.
- Nanoparticle and Inorganic ReagentsNon-viral carriers made from materials like gold nanoparticles, silica, calcium phosphate, or magnetic nanoparticles.
- Extracellular Vesicles (EVs)Naturally secreted, nanosized vesicles released by cells that carry proteins, lipids, and nucleic acids.