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721 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Antigen-specific T-cell response Clear keyword

Vaccine2026ResearchNon-viral Gene DeliveryDrug Delivery

1. mRNA-LNP vaccines targeting mutation-derived BRCA2 and p53 elicit antigen-specific immune responses in beagles

Lee Y, Lee J, Oh Ey, Kim Y, Jo S, Yoon S, Et Al.

Messenger RNA (mRNA) vaccines are next-generation platforms capable of eliciting potent cellular and humoral immunity through intracellular expression of tumor-associated or mutation-specific antigens. Canine mammary gland tumor (CMT), commonly encountered in female dogs, frequently harbors mutations in the BRCA2 and…

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