Publications
Reviews, data and technical documents
Our literature reviews, company and field news, and downloadable white papers, application notes and conference posters.
Articles
All articles →Literature reviews
- Advances in lipids design for LNP-mediated DNA and RNA deliveryAdvances in Colloid and Interface Science
- Recent Developments in Lipid Nanoparticle-Mediated Delivery of Biotherapeutics and Gene Therapy Across the Blood-Brain BarrierBioDrugs
- Recent Advances in Lipid Nanoparticles: Nucleic Acid Therapeutics and Targeting StrategiesSmall
- Rational design of lipid nanoparticles for enabling gene therapiesMolecular Therapy Methods & Clinical Development
- The 60-year evolution of lipid nanoparticles for nucleic acid deliveryNature Reviews Drug Discovery
- Beyond Lipids: Exploring Advances in Polymeric Gene Delivery in the Lipid Nanoparticles EraAdvanced Materials
Downloads
Download library →White papers
Design rules and platform overviews for formulation scientists and programme leads.
- BrilliantCore™ platform technical briefFormulation principles, lipid library composition and characterisation data for our ionisable carrier series.PDF · 2 pages ↓
- Engineering endosomal escape: design rules for ionisable lipid nanoparticlesWhy most internalised cargo never reaches the cytosol, and how pKa, lipid shape and helper lipids change that.PDF · 2 pages ↓
- Targeting ligand selection for nanocarriersA practical comparison of antibody fragments, affibodies, aptamers and peptides for surface functionalisation.PDF · 2 pages ↓
Downloads
Download library →Application notes
Step-by-step methods with acceptance criteria you can run in your own laboratory.
- Controlling LNP size and PDI with microfluidic mixingHow total flow rate and flow-rate ratio set particle size, with a worked design-of-experiments example.PDF · 1 page ↓
- Measuring mRNA encapsulation efficiency with a RiboGreen assayA plate-based protocol with Triton X-100 lysis, standard curves and common sources of error.PDF · 2 pages ↓
- Testing pH-triggered charge reversal in tumour-responsive carriersZeta-potential titration and uptake assays that confirm a carrier switches charge in mildly acidic conditions.PDF · 1 page ↓
Downloads
Download library →Conference posters
Research summaries presented at scientific meetings, in poster format.
- pKa tuning of ionisable lipids and cytosolic delivery of siRNAPoster summarising how apparent pKa relates to gene silencing in hepatocyte and tumour cell models.PDF · 1 page ↓
- A multiplexed quantum-dot biomarker panel for point-of-care usePoster describing the optical design and analytical performance of a twelve-channel quantum-dot immunoassay.PDF · 1 page ↓
Let's engineer the next delivery breakthrough together
We co-develop nanocarrier and biosensing programmes with pharma, biotech and academic groups — from target selection through GMP supply.
ResearchersRequest a technical consultationTalk formulation, characterisation or assay design with one of our scientists.Industry partnersExplore co-developmentFeasibility studies, co-development programmes, licensing and GMP supply.InvestorsDownload our capabilities deckPlatform, pipeline milestones, manufacturing and partnership models in one PDF.
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