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Research Review

Showing 1–1 of 1 articles · Keyword: Bayesian optimization Clear keyword

Biotechnology and bioengineering2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Serotype-Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno-Associated Viral Vectors

Minzoni A, Shastry S, Barbieri E, Hurst Mr, Idanwekhai K, Wu Y, Et Al.

Adeno-associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized. This…

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