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586 articles

Research Review

Showing 1–1 of 1 articles · Keyword: CAR-T cell engineering Clear keyword

Biomedicines2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Lipid Nanoparticle Delivery of CAR276 mRNA Enables Antigen-Specific Cytotoxicity in T Cells Against Glioblastoma Cells

Zahedipour F, Sadeghianfard S, Wisser S, Dinarvand M, Steiner D, Ramesh A, Et Al.

Background/Objectives: Glioblastoma multiforme (GBM) remains the most aggressive and treatment-refractory primary brain tumor, with current therapeutic modalities providing minimal survival improvement. Chimeric antigen receptor (CAR)-based immunotherapies succeeded in hematologic malignancies but are constrained in…

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