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646 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Dosimetry Clear keyword

International journal of pharmaceutics: X2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Microliter-scale in vitro aerosol-cell delivery of inhalable antisense oligonucleotide (ASO) induces "burst-like" pharmacokinetics

Kumar P, Chakraborty A, Richter E, Yang L, Schröppel A, Mergault C, Et Al.

Unlike traditional submerged cell cultures, nebulized drug delivery to air-liquid interface (ALI)-cultured lung cells provides a clinically relevant route for in vitro testing of inhalable drugs. Current nebulizer systems deliver non-physiologically large drug volumes. Here, we introduce the Cloud MAX technology…

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