1. Biomimetic Nanoparticles With Overexpressed Adhesion Proteins for Targeted Delivery of Gambogic Acid in Hepatocellular Carcinoma
Zhang Y, Yang M, Wu Y, Zhang Y, Xu J, Zheng J, Et Al.
Cancer cell membrane coating offers a promising strategy for targeted drug delivery, yet its homotypic targeting mechanism and optimization remain insufficiently understood. This study identifies epithelial cell adhesion molecule (EpCAM), rather than Galectin-3, as the pivotal mediator of homologous uptake in…
- Biomimetic nanoparticles
- Cell membrane coating
- Clathrin‐mediated endocytosis
- EpCAM overexpression
- Homologous tumor targeting
