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Research Review

Showing 25–25 of 25 articles · Keyword: Nucleic acids Clear keyword

ReviewNon-viral Gene Delivery

25. Delivery of therapeutic nucleic acids via transferrin and transferrin receptors lipoplexes and other carriers

The transferrin receptor (TfR) is overexpressed on many cancer cells and is efficiently internalised, making it a useful target for delivering small-molecule drugs and nucleic acid therapeutics while reducing non-target effects. The review summarises TfR biology, Tf-lipoplex development, and therapeutic applications…

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