Nanomedicine : nanotechnology, biology, and medicine2026ResearchDrug Delivery
1. Fucoidan-functionalized liposomal nanocarriers for targeted miR-217-5p delivery and combined antitumor treatment in pancreatic ductal adenocarcinoma
Tan C, Fang Y, Guo R, Zheng Z, He M, Yang J, Et Al.
The clinical translation of microRNA (miRNA) therapy is hindered by poor tumor specificity and inefficient delivery. In this study, we constructed a targeted nanoplatform using marine sulfated polysaccharide fucoidan (FU) to encapsulate miR-217-5p in FU-modified cationic liposomes (FU-LIP-miR) for the treatment of…
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