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661 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Small molecule inhibitors (SMIs) Clear keyword

Journal of controlled release : official journal of the Controlled Release Society2026ResearchDrug Delivery

1. Dual drug delivery via integrin-targeted nanoparticles enhances therapeutic efficiency in BRAFV600E colon cancer

Sen R, Alnatour M, Janardhanam Lsl, Anjum Mm, Naguib Yw, Geary Sm, Et Al.

Colorectal cancer (CRC) patients possessing the BRAF V600E mutation often fail to respond to current first line therapies and are associated with poor prognosis, despite the advent of orally delivered small molecule inhibitors (SMIs) targeting the RAS-RAF-MEK-ERK signaling pathway. Thus, further improvements are…

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