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586 articles

Research Review

Showing 1–1 of 1 articles · Keyword: liquid chromatography Clear keyword

Angewandte Chemie (International ed. in English)2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2-Ethyl-2-Oxazoline) (PEtOx) for Organic Solvent-Free Lipid Nanoparticle Formulations

Streiber M, Holick Ct, Gath L, Tsarenko E, Bachmann V, Litsiou S, Et Al.

Efficient, biocompatible, and flexible application of CRISPR-Cas9 remains a major challenge in gene therapy. This study addresses a novel formulation method, focusing on organic solvent-free lipid nanoparticles for the efficient delivery of CRISPR-Cas9 components. Therefore, novel stealth lipids comprising the lipid…

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