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586 articles

Research Review

Showing 1–1 of 1 articles · Keyword: mRNA degradation Clear keyword

ACS nano2026ResearchNon-viral Gene DeliveryDrug Delivery

1. In Vivo Blood Kinetics and Transcript Integrity of Three mRNA-Lipid Nanoparticle Vaccines in Humans

Kent Sj, Li S, Amarasena Th, Reynaldi A, Leeming Mg, Juno Ja, Et Al.

mRNA-lipid nanoparticle (LNP) vaccines are detectable in human blood after vaccination, but platform-specific differences in systemic persistence and transcript integrity remain poorly defined. We analyzed serial blood samples from 73 participants receiving Moderna mRNA-1273 (three formulations), Pfizer/BioNTech…

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