ACS nanoscience Au2026ResearchNon-viral Gene DeliveryDrug Delivery
1. Lipid Nanoparticles at the Crossroads of Chemistry and Medicine: A Tutorial
Rogado Mt, Wang A, Zeng S, Wang Z, Burda C
Lipid nanoparticles (LNPs) have risen to the forefront of modern therapeutics by enabling the clinical success of COVID-19 mRNA vaccines. In order for them to function as drug delivery vesicles, LNPs must have scalable, tunable, and targeted nanoscale platforms whose strengths in versatility, performance, and…
- cellular uptake
- endosomal escape
- gene therapy
- lipid nanoparticles (LNPs)
- nanoparticles
- nanoplatform technology
- payload encapsulation
- targeted drug delivery
