1. Preparation and comprehensive physicochemical characterization of trastuzumab-loaded PEGylated liposomal nanoparticles for systemic delivery
Abbas Ss, Hassan Bar, Hadi Ha, Mohammed Ah, Alsammarraie Aza, Al-Bayati Ma
ObjectiveThe primary objective of this experimental formulation-development study was to prepare and physicochemically characterize a trastuzumab-loaded liposomal formulation containing post-inserted DSPE-PEG2000 for systemic-delivery research. The secondary objective was to determine whether the preparation and…
- HER2
- PEGylated liposomes
- monoclonal antibody delivery
- physicochemical characterization
- protein integrity
- systemic nanomedicine
- trastuzumab
