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586 articles

Research Review

Showing 1–1 of 1 articles · Keyword: vulnerable plaques Clear keyword

Nano letters2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Piperazine-Structured Lipid Nanoparticles Enable Enhanced Targeted Delivery of SHP-1 siRNA to Macrophages for Treatment of Atherosclerotic Vulnerable Plaques

Zhu P, Huang Y, Pan L, Leng Y, Zheng H, Zhou Y, Et Al.

Atherosclerotic vulnerable plaques pose a risk for acute coronary syndrome and sudden cardiac death due to plaque rupture and thrombosis. While nanomedicines modulating macrophage functions have attracted intensive interest, efficient delivery to plaque macrophages remains challenging. Here, mannose-modified lipid…

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