1. Aptamer-functionalized exosomes co-delivering miR-934 inhibitor and gemcitabine for targeted pancreatic cancer therapy
Bi J, Ye L, Shi H, Jian Z, Li R, Jiang Z, Et Al.
Pancreatic cancer remains a malignancy with limited treatment efficacy and high resistance to chemotherapy. miR-934 was identified as an oncogenic miRNA significantly upregulated in pancreatic cancer, promoting tumor progression, epithelial-mesenchymal transition (EMT), and chemoresistance by targeting the tumor…
- Epithelial-mesenchymal transition (EMT)
- Exosome drug delivery
- Gemcitabine
- PRUNE2
- Pancreatic cancer
- miR-934
