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571 articles

Research Review

Showing 1–1 of 1 articles · Keyword: IκBα Clear keyword

Molecular pharmaceutics2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Combined siRNA Targeting IκBα and Stat6 Promotes Macrophage Reprogramming toward Cancer Immunotherapy

Gul S, Vergnaud J, Wang Q, Hery M, Dumont F, Tran P, Et Al.

Tumor-associated macrophages (TAMs) are central regulators of the tumor microenvironment (TME). Their polarization state can critically influence tumor development and treatment resistance. In the TME, the pro-tumor M2-like phenotype is the most prevalent among TAMs and contributes to tumor progression by promoting…

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