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Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

706 articles

Showing 1–2 of 2 articles · Keyword: Immunotherapy Clear keyword

Journal of nanobiotechnology2026ResearchDrug Delivery

1. Manganese dioxide-entrapping dendrimers as a therapeutic peptide vaccine for combined tumor chemodynamic/immune therapy and tumor prevention

Xia L, Wang J, Li A, Li Y, Liu J, Shi X, Et Al.

Developing a vaccine that can both elicit robust antitumor immune responses and exert potent tumoricidal effects remains a formidable challenge. Herein, we design a functional dendrimer nanocarrier to co-deliver manganese dioxide (MnO 2 ) nanoparticles (NPs) and ovalbumin peptide antigen OVA 257-264 for synergistic…

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Journal for immunotherapy of cancer2026ResearchNon-viral Gene DeliveryDrug Delivery

2. IL7R mRNA therapy enhances antitumor T cell immunity and suppresses tumor growth in preclinical tumor models

Rehman Au, Khan Mn, Akhtar A, Qin Q, Zhang X, Asghar Ma, Et Al.

Interleukin-7 receptor (IL7R) signaling is critical for T-cell survival, homeostasis, and immune function, but the therapeutic potential of increasing IL7R expression through messenger RNA (mRNA) delivery remains poorly defined. We investigated whether IL7R mRNA therapy could enhance antitumor immunity and improve…

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