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Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

691 articles

Research Review

Showing 1–2 of 2 articles · Keyword: Intracellular trafficking Clear keyword

Neoplasia (New York, N.Y.)2026ResearchDrug Delivery

1. αvβ3 integrin recycling is associated with the intracellular trafficking and efflux of cRGDfK-modified PLGA nanoparticles

Zhu J, Chen S, Yu L, Xu R, Sun H, Wang X, Et Al.

Understanding the cellular transport mechanisms of active-targeting nanocarriers is essential for improving their therapeutic performance. In this study, cRGDfK-modified poly(lactic-co-glycolic acid) nanoparticles (cRGDfK-PLGA-NPs) were developed as an αvβ3 integrin-targeted delivery system, and their cellular…

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Pharmaceutics2026ReviewDrug Delivery

2. Beyond Uptake in Cancer Lipid Nanomedicines: Linking Tumour Access, Intracellular Fate, and Molecular Action

Syed Hashim Sa

Clinical translation of lipid nanomedicines in oncology is limited by biological barriers and by an interpretive challenge: tumour accumulation and cellular uptake are often used as proxies for delivery even when pharmacologically competent cargo, meaning cargo capable of producing its intended molecular effect, has…

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