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571 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Ionizablelipids Clear keyword

International journal of pharmaceutics2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Disulfide bond-modified ionizable lipids for co-delivery of siRNA and carbon dots in the treatment of acute liver injury

Chu R, Shen Z, Pan T, Gao Q, Wang Z, He J

Acute liver injury (ALI) is a severe clinical condition characterized by excessive oxidative stress and inflammatory responses, for which effective targeted therapeutic strategies remain limited. In this study, a redox-responsive ionizable lipid (Lipid S) was designed by incorporating a disulfide bond into its…

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