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586 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Machine learning Clear keyword

International journal of pharmaceutics2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Machine learning-guided chondrocyte membrane-camouflaged lipid nanoparticles for intra-articular SOX9 mRNA therapy of osteoarthritis

Li J, Li C, Wang H, Yu H, Zhang T, Li C, Et Al.

Osteoarthritis (OA) progression involves cartilage matrix loss and persistent inflammation. This study developed a machine learning-guided and chondrocyte membrane-camouflaged lipid nanoparticle carrying messenger RNA (CM-LNP@mRNA) platform for intra-articular SOX9 delivery. Random forest analysis identified the…

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