Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.
391 articles
D Zhi, A Halemaimaiti, B Dai, H Li, H Wang, Z Zhang, J Yu, S Zhang
This review examines how lipid structure and formulation affect the delivery of DNA, mRNA and siRNA by lipid nanoparticles, while assessing tissue targeting, safety and clinical translation challenges.
Read the articleU Iqbal, Rw Hwang, Wj Costain
A review of blood–brain barrier transport mechanisms and emerging lipid nanoparticle strategies for carrying nucleic acid and other complex therapies into the central nervous system.
S Sarmah, S Baidya, M De
This review surveys lipid nanoparticle composition, ionizable lipid synthesis and strategies to target delivery of fragile RNA therapeutics while addressing tissue selectivity and immune activation.
Read the articleCa Brimacombe, Ja Kulkarni, Mhy Cheng, K An, D Witzigmann, Pr Cullis
A review of the physical principles and development history behind siRNA lipid nanoparticles for liver gene silencing and mRNA lipid nanoparticles for protein expression.
Read the articlePr Cullis, Pl Felgner
This historical review traces lipid-based gene delivery from cationic lipoplexes to ionizable lipid nanoparticles, connecting foundational research with approved mRNA vaccines and siRNA therapy.
We co-develop nanocarrier and biosensing programs with pharma, biotech and academic groups — from target selection through GMP supply.
