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571 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Myocardial ischemia-reperfusion injury Clear keyword

Materials today. Bio2026ResearchDrug Delivery

1. Novel modifications of small extracellular vesicles to enhance cardiac-specific delivery of siPKA RNA and edaravone against ischemia-reperfusion cardiac injury

Pei X, Li R, Bai Y, Yan Q, Qi X, Jiao W, Et Al.

Relative tight endothelium in the heart may be a barrier for drugs in the large molecule and nanoparticle formats to act on cardiomyocytes. We hypothesize that enhanced binding of large molecules or nanoparticles to the cardiac capillary endothelial cells can increase the transendothelial transport of these drugs to…

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