1. Integrating Nanomaterials with Extracellular Vesicles: Engineering Strategies and Translational Perspectives
Le Th, Phan Lmt
Extracellular vesicles (EVs), particularly stem cell-derived exosomes, serve as vital natural nanocarriers in regenerative medicine, immune modulation, and targeted drug delivery due to their innate ability to transport bioactive cargo across complex biological barriers. Despite this potential, the therapeutic efficacy of native EVs is frequently constrained by intrinsic limitations such as rapid systemic clearance, low loading efficiency, limited targeting specificity, and significant manufacturing hurdles.
Read the article