1. Cell and Gene Therapy in Lung Transplantation: From Experimental Promise towards Clinical Translation
Olm F, Kortleven P, Mittendorfer M, Carlon Ms, Ceulemans Lj, Lindstedt S
Lung transplantation (LTx) remains the only definitive therapy for selected patients with end-stage lung disease, yet outcomes are limited by early ischemia-reperfusion injury (IRI) and primary graft dysfunction (PGD), and by chronic lung allograft dysfunction (CLAD) as the leading cause of late graft failure.
- Cell and gene therapy
- Ex vivo lung perfusion (EVLP)
- Ischemia-reperfusion injury (IRI)
- Lung transplantation
- Primary graft dysfunction (PGD)
