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Research Review

Showing 1–1 of 1 articles · Keyword: UHPLC-ELSD Clear keyword

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Development of combined bio-RP-HPLC-UV and UHPLC-ELSD methods for quantitation of mRNA-LNP content before and after size-exclusion chromatography

Sun T, Wu Q, Liu X, Xing Z, Shi L, Hu F, Et Al.

Following the COVID-19 pandemic, mRNA vaccines have been widely deployed, with lipid nanoparticles (LNPs) serving as the prevailing delivery vehicles for mRNA vaccines. Separation and quantitative determination of mRNA and LNP lipid components have therefore attracted considerable attention. Reported mRNA assays…

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