Drug development research2026ResearchNon-viral Gene DeliveryDrug Delivery
1. Preclinical Evaluation of cRGD-Functionalized Lipid-Polymer Hybrid Nanocarriers for Anti-VEGF Gene Therapy in Triple-Negative Breast Cancer
Cesur Ergun B, Demir-Dora D
Triple-negative breast cancer (TNBC) remains one of the most aggressive breast cancer subtypes owing to its high metastatic potential and the absence of effective molecularly targeted therapies. Although cRGD-functionalized nanocarriers have been extensively investigated for TNBC treatment, most reported systems…
- antiangiogenic therapy
- antitumor activity
- lipid polymer hybrid nanoparticle
- targeted gene therapy
- triple negative breast cancer
