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Research Review

Showing 1–1 of 1 articles · Keyword: biomimetic nanovesicles Clear keyword

International journal of nanomedicine2026ResearchDrug Delivery

1. Hybrid Liposome-U87MG Membrane Nanovesicles Enhance Brain Delivery and Therapeutic Efficacy of Irinotecan in Orthotopic Glioma

Li S, Sun Y, Liu Y, An Q, Liu C, Cui H, Et Al.

The blood-brain barrier (BBB) and hydrolytic inactivation of the lactone form limit the efficacy of irinotecan (CPT-11) against glioma. To address these challenges, we developed a CPT-11-loaded hybrid liposome-U87MG cell membrane nanovesicle formulation (Hybrid/CPT-11), an underexplored biomimetic strategy for glioma…

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