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601 articles

Research Review

Showing 1–1 of 1 articles · Keyword: glioma Clear keyword

Frontiers in immunology2026ReviewNon-viral Gene DeliveryDrug Delivery

1. Intranasal nano-immunotherapy for glioma: bypassing the blood-brain barrier, reprogramming the immune microenvironment, and bridging preclinical validation

Li L, Wu M, Li L

Glioma, particularly glioblastoma, remains difficult to treat because of limited drug penetration across the blood-brain barrier, profound immune suppression, and insufficient intracranial exposure of systemic immunotherapies. Intranasal nano-immunotherapy is being explored as a potential strategy that may integrate…

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