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Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

616 articles

Research Review

Showing 1–2 of 2 articles · Keyword: brain targeting Clear keyword

International journal of nanomedicine2026ReviewDrug Delivery

1. An Update on Blood-Brain Barrier Penetrating Nanoparticles for the Treatment of Glioblastoma

Mcgranaghan Ct, Vankeulen-Miller R, Fenton Os, Mcerlean Em

Glioblastoma (GBM) is an aggressive and lethal primary brain malignancy, with patient survival largely unchanged over recent decades despite advances in surgery, radiotherapy and chemotherapy. A major therapeutic challenge is the blood-brain barrier (BBB), which restricts the delivery of many systemically…

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Journal of liposome research2026ResearchDrug Delivery

2. Rational design and characterisation of intranasal gel incorporating eletriptan HBr-loaded solid lipid nanoparticles for enhanced brain delivery in migraine

Budharam S, Shivally Boregowda S, Binsuwaidan R, Adnan M, Alshammari N, Almarshadi F, Et Al.

Eletriptan HBr-loaded solid lipid nanoparticles (ESLN) were designed for brain delivery by circumventing first-pass metabolism and the blood-brain barrier. The formulation combines biocompatible polymers with the permeability-enhancing properties of lipids. A central composite design was employed to optimize…

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