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Research Review

Showing 1–1 of 1 articles · Keyword: brain targeting Clear keyword

Journal of liposome research2026ResearchDrug Delivery

1. Rational design and characterisation of intranasal gel incorporating eletriptan HBr-loaded solid lipid nanoparticles for enhanced brain delivery in migraine

Budharam S, Shivally Boregowda S, Binsuwaidan R, Adnan M, Alshammari N, Almarshadi F, Et Al.

Eletriptan HBr-loaded solid lipid nanoparticles (ESLN) were designed for brain delivery by circumventing first-pass metabolism and the blood-brain barrier. The formulation combines biocompatible polymers with the permeability-enhancing properties of lipids. A central composite design was employed to optimize…

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