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601 articles

Research Review

Showing 1–1 of 1 articles · Keyword: cell identity Clear keyword

Epigenomics2026ReviewNon-viral Gene DeliveryDrug Delivery

1. Synthetic mRNA engineering beyond prophylactic infectious disease vaccines: epigenomic and molecular reprogramming of diseased cells

Mustafa Am, Kareem Si, Raouf Cg, Ahmed Sm

The clinical validation of mRNA-based COVID-19 vaccines in 2020-2021 accelerated the development of synthetic messenger RNA as a precision therapeutic platform beyond infectious disease prevention. Unlike gene therapy approaches that permanently modify genomic DNA, synthetic mRNA enables transient protein expression…

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