AAPS PharmSciTech2026ReviewDrug Delivery
1. Ligand-modified Lipid-based Drug Delivery Vehicles for the Selective Targeting of Cancerous Cells
Eknure C, Kumar M, Bachhav Y
Chemotherapy is widely recognized as the mainstay of cancer therapy; however, its lack of specificity and off-target toxicities limit therapeutic success. The lipid-based nanocarriers with targeting ligands such as folic acid, transferrin, aptamers, and antibodies are widely recognized as effective for cancer cell…
- active targeting
- artificial intelligence
- ligand-modified lipid nanoparticles
- ligand-targeted drug delivery
- protein corona
