Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

571 articles

Research Review

Showing 1–3 of 3 articles · Keyword: mRNA vaccine Clear keyword

Vaccine2026ResearchNon-viral Gene DeliveryDrug Delivery

1. mRNA encoding norovirus VP1 produces antigenically functional virus-like particles in vitro

Reyes Ballista Jm, David C, Pirrone A, Gonzalez-Fernandez E, Wei J, Wen Z

Human norovirus is a leading cause of acute gastroenteritis worldwide across all age groups, yet no licensed vaccine is available. The major capsid protein, VP1, self-assembles into highly immunogenic virus-like particles (VLPs) that have shown promise in clinical studies. Recently, mRNA has emerged as a compelling…

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Theranostics2026ResearchNon-viral Gene DeliveryDrug Delivery

2. mRNA-dendritic cell antigen vaccine potentiates CD38 CAR-T Cell therapy for relapsed/refractory acute myeloid leukemia

Lu Y, Cai X, Li Y, Lv Y, Tang Y, Li Y, Et Al.

Chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising strategy for management of relapsed/refractory acute myeloid leukemia (R/R AML). Safety and preliminary activity of CD38-targeted CAR-T cells in R/R AML were demonstrated in our prior study; however, relapse with CD38-positive blasts persisted…

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Frontiers in oncology2026ReviewNon-viral Gene DeliveryDrug Delivery

3. Progress on therapeutic mRNA vaccines for cancer

Wu S, Liao H, Zhang W

Therapeutic mRNA vaccines are a clinically validated cancer immunotherapy platform using in vitro transcribed mRNA encoding tumor antigens to induce durable anti-tumor immunity. Advances in mRNA engineering, lipid nanoparticle (LNP) delivery, and immunomodulatory combinations have propelled this approach from…

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