Frontiers in immunology2026ReviewDrug Delivery
1. Extracellular vesicle-based drug delivery in pediatric immune thrombocytopenia
Di Domenico O, Marrapodi Mm, Di Feo G, Argenziano L, Rossi F, Di Paola A
Pediatric immune thrombocytopenia (ITP) is an acquired immune-mediated disorder triggered by autoantibody production directed against glycoproteins on the platelet surface, leading to platelet destruction in the spleen and impaired megakaryopoiesis in the bone marrow. The immune response is further compromised by a…
- cell-free therapy
- drug delivery
- extracellular vesicles
- immune thrombocytopenia
- immunomodulation
- mesenchymal stromal cells