International journal of nanomedicine2026ResearchDrug Delivery
1. Pomegranate Seed Oil Biologically Engineered Lactobacillus Extracellular Vesicles with Enhanced Yield and Brain Delivery via ApoE-Enriched Protein Corona
Duan D, Xu S, Wu K, Xu M, Zhou S, Yang X, Et Al.
The blood-brain barrier (BBB) is a major bottleneck for nanomedicine-based treatment of central nervous system (CNS) disorders. Lactobacillus -derived extracellular vesicles (LEV) are promising biocompatible nanocarriers, but their low production yield and limited BBB permeability hinder their development. We…
- Alzheimer’s disease
- Lactobacillus extracellular vesicles
- brain delivery
- membrane engineering
- pomegranate seed oil
- protein Corona
