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Journal of liposome research2026ResearchNon-viral Gene Delivery

1. Optimized cationic lipid microbubbles for ultrasound-triggered gene delivery: formulation, characterization, and in vitro evaluation

Chen S, Wei W, Xing Q, Li W, Feng X, Mai P, Et Al.

The clinical efficacy of non-viral gene therapy is often limited by the low loading capacity of delivery vectors. To address this, we engineered an ultrasound-responsive cationic lipid microbubbles (CLMBs) platform from clinically accepted biocompatible components to maximize nucleic acid encapsulation. The system…

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