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676 articles

Research Review

Showing 1–1 of 1 articles · Keyword: thermostability Clear keyword

Advanced science (Weinheim, Baden-Wurttemberg, Germany)2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Spray-Dried mRNA-LNP Powder Enabling Multi-Route Delivery With 3-Year Refrigerated Stability

Sarode A, Patel P, Derosa F, Karve S, Gervier R

The clinical translation of mRNA-lipid nanoparticle (mRNA-LNP) therapeutics is constrained by limited stability of liquid formulations, necessitating ultra-cold storage and restricting global accessibility. Here, we report a spray-dried dry powder platform for mRNA-LNPs that overcomes these limitations while enabling…

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