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661 articles

Research Review

Showing 1–1 of 1 articles · Keyword: IgA Clear keyword

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V2026ResearchDrug Delivery

1. Lipid nanoparticles adjuvanted with poly(I:C) enhance respiratory mucosal immunity induced by a protein subunit vaccine

Da Costa Rodrigues T, Kola Ns, Patel D, Ibrahim A, Ma'aruf Sy, Haddadi A, Et Al.

Subunit vaccines are typically given through injections, which limits mucosal immunity. Most adjuvants do not stimulate mucosal responses but using lipid nanoparticles (LNPs) encapsulating polyinosinic-polycytidylic acid (poly(I:C)), a toll-like receptor 3 agonist, could enhance the immune response in the lungs. We…

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