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691 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Intracellular barriers Clear keyword

Biochemical pharmacology2026ReviewNon-viral Gene Delivery

1. Strategies for overcoming extracellular and intracellular delivery barriers in Liver-Targeted gene therapy

Yang J, Zhang J, Jiang J, Liang G, Li Z

Liver-targeted gene therapy holds great potential for treating diverse hepatic disorders, yet its efficacy is significantly hindered by complex extracellular and intracellular delivery barriers. This review systematically delineates the pathophysiological obstacles that impede the efficient delivery of nucleic acid…

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