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691 articles

Research Review

Showing 1–1 of 1 articles · Keyword: LNPs Clear keyword

Journal of controlled release : official journal of the Controlled Release Society2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Selective ORgan-targeting lipid nanoparticles deliver SMAD7 mRNA to fibrotic lungs and attenuate pulmonary fibrosis

Kim M, Jeong M, Chatterjee S, Vaidya A, Pham C, Lee Sm, Et Al.

Fibroblast activation and differentiation into myofibroblasts drive excessive extracellular matrix deposition and irreversible scarring in pulmonary fibrosis, such as idiopathic pulmonary fibrosis (IPF), underscoring the need for therapies that directly target fibroblast activation. Here, we apply engineered…

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