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571 articles

Research Review

Showing 1–1 of 1 articles · Keyword: Oral delivery Clear keyword

ACS nano2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Targeted Gastrointestinal Delivery of mRNA Lipid Nanoparticles Enables Systemic Vaccination and Glucagon-like Peptide-1 Metabolic Therapy

Abbas Am, Ghanim R, Rudden S, Schultz D, Jang B, Shakked A, Et Al.

Lipid nanoparticles (LNPs) administered parenterally often show poor localization to multiple tissue types, including the pancreas and gastrointestinal (GI) tract. Furthermore, patients typically prefer orally administered drugs to those that are given parenterally. We therefore investigated whether GI LNP…

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