1. Selective ORgan-targeting lipid nanoparticles deliver SMAD7 mRNA to fibrotic lungs and attenuate pulmonary fibrosis
Kim M, Jeong M, Chatterjee S, Vaidya A, Pham C, Lee Sm, Et Al.
Fibroblast activation and differentiation into myofibroblasts drive excessive extracellular matrix deposition and irreversible scarring in pulmonary fibrosis, such as idiopathic pulmonary fibrosis (IPF), underscoring the need for therapies that directly target fibroblast activation. Here, we apply engineered…
Read the article