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Showing 1–1 of 1 articles · Keyword: Uni-vector system Clear keyword

Methods in molecular biology (Clifton, N.J.)2027ResearchNon-viral Gene Delivery

1. Improvement of Genome Editing Efficiency in Mammalian Cells by a Refined Uni-Vector Prime Editing System

Liao Lz, Wu Kj

Prime editing is an advanced technology in the CRISPR/Cas genome editing field. The original multi-vector method utilized in prime editing has less efficiency and precision and is also inherently difficult in generating homozygous mutations in mammalian cells. To overcome these technical difficulties, a Uni-vector…

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