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Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

661 articles

Research Review

Showing 1–2 of 2 articles · Keyword: biological barriers Clear keyword

Biomacromolecules2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Modular Peptide Coatings Regulate the Multistep Biological Performance of Lipid Nanoparticles for Enhanced mRNA Delivery

Tang C, Ye Y, Min J, Han M, Jiao X, Su R, Et Al.

Lipid nanoparticles (LNPs) are a leading platform for mRNA delivery, yet improving their performance often requires complex chemical modification or reformulation of core components. Here, we report a modular peptide-coating strategy for post-formulation engineering of LNP interfaces through physical assembly. A…

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International journal of pharmaceutics: X2026ReviewDrug Delivery

2. Precision engineering of nanocarriers for transport across complex biological barriers

Acharya R, Komedchikova E, Choi Y, Yang J, Kim J, Son J, Et Al.

Biological barriers are essential for maintaining tissue homeostasis and protecting organs from harmful external agents; however, they also represent major obstacles to the efficient delivery of therapeutic agents. The blood-brain barrier, ocular barriers, mucosal barriers, and vascular endothelial barriers exhibit…

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