International journal of nanomedicine2026ReviewDrug Delivery
1. Organelle-Targeted Nanocarriers for Cancer Therapy: Design Principles, Intracellular Trafficking, and Translational Barriers in Precision Drug Delivery
Zhang H, Guo J, Wang X, Shen Y, Yao Y, Ghadage Ss, Et Al.
The clinical translation of cancer nanomedicine remains constrained by inefficient intracellular delivery, poor subcellular specificity, and limited tumor accumulation, highlighting the need for more precise drug delivery strategies. Organelle-targeted nanocarriers have emerged as a promising platform for enhancing therapeutic efficacy by directing drugs to specific intracellular compartments, including the nucleus, mitochondria, lysosomes, and endoplasmic reticulum.
cancer treatmentendoplasmic reticulumgolgi apparatuslysosomenano-drugsorganelle-targeted mitochondrion therapyorganelle-targeted nucleus therapy
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