Papers, explained in our own words

1. Advances in Peptide-Functionalized Polymeric Nanocarriers for Cancer Therapy

Ommi O, Covarrubias-Zambrano O, Bossmann Sh, Kamath D

Background/Objectives: Peptide-functionalized polymeric nanocarriers are redefining targeted cancer therapy by combining the molecular specificity of peptides with the structural versatility of polymers. This review aims to highlight recent advances in peptide-functionalized polymeric nanocarrier systems designed to…

• cancer
• cell-penetrating peptides
• nanocarriers
• polymer
• targeting peptides
• therapeutic peptides
• tumor-microenvironment

2. Liposomal Delivery Systems: Design Optimization and Current Applications

Liposomes are attractive pharmaceutical carriers because they encapsulate hydrophilic and hydrophobic drugs and are biocompatible and biodegradable. However, conventional liposomes suffer from aggregation/fusion, premature payload release, rapid clearance by the mononuclear phagocyte system (MPS), low entrapment…

• Liposomes
• siRNA
• Peptides
• Nucleic acids
• Lipid nanoparticle
• Endosomal escape
• Cell-penetrating peptides