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616 articles

Research Review

Showing 25–25 of 25 articles · Keyword: micelles Clear keyword

Journal of Controlled Release2007ReviewNon-viral Gene Delivery

25. Polymer-based siRNA delivery Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery

Gary, D. J.; Puri, N.; Won, Y.-Y

Polymer-based siRNA delivery is promising but faces limitations similar to polymer-based DNA delivery, yet the two nucleic acids differ fundamentally in size, stiffness, stability, site of action, and duration of effect. This review addresses the need to understand these distinctions so that knowledge from the…

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