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Research Review

Showing 1–1 of 1 articles · Keyword: pH-responsive systems Clear keyword

Expert opinion on drug delivery2026ReviewNon-viral Gene Delivery

1. Microenvironment-guided design of non-viral gene delivery systems: from biological cues to therapeutic translation

Mohammad Gholinia Sarpoli L, Hamblin Mr, Ebrahimifard M

Non-viral gene delivery systems offer adaptable alternatives to viral vectors for gene therapy. Nevertheless, their clinical translation remains limited by biological barriers and the pathological tissue microenvironment. Tumors exhibit alterations in the tissue microenvironment, including extracellular acidosis…

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